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Vol 42, No 4 (2025)

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Authors in this issue:

AFMN Biomedicine Editorial Board, Aleksandar Popović, Aleksandar Skakić, Aleksandra Stojanović, Ali Sadeghi, Ana Cvetanović, Ana Stojković, Anahita Babaei, Andrej Veljković, Andrii Sidorov, Andrija Jović, Anđela V. Dragićević, Arina Ivanitsa, Behnaz Souizi, Bojana Miladinović, Danijela Jezdimirović, Dmytro Grebeniuk, Dragana R. Pavlović, Dragoslav Bašić, Dušan Sokolović, Dušanka Kitić, Eleftheria Papadopoulou, Goran Čolaković, Gordana Kocić, Ina Konstantinović, Irena Ćojbašić, Irena Conić, Iuliia Pashkova, Ivan Petković, Javad Rezanezhad, Jovan Hadži-Đokić, Jovana Milosavljević, Katarina Pavlović Jugović, Katarina Simonović, Konstantinos Leivaditis, Ljubomir Dinić, Mahsa Afrand, Maja Nikolić, Marzie Torkmannejad Sabzevari, Mehrnaz Mehrdoost, Milan Petković, Milena Maričić, Milena Popović, Milica Veljković, Milica Milutinović, Milica Radić, Milica Randjelović, Miloš Stepović, Miodrag Stanković, Miodrag Vučić, Mirahmad Hendinezhad, Mohsen Ziyaeifard, Nahid Aghdaii, Narjes Forouhar, Nikola M. Stojanović, Nikolina Savić, Nina Medojević, Niusha Rostampur, Ognjen Radović, Oleksandr Smiiukha, Pouriya Nekoueifard, Rasool Ferasatkish, Rasoul Azarfarin, Roberta Marković, Shahla Ansari, Slađana Anđelić, Stefanos Roumeliotis, Svitozar Prevar, Tanja Džopalić, Tanja Nikolić, Vanja Pažun, Verica Trbović, Vita Ruzhanska, Yuriy Hnatiyk, Zahra Soheilirad, Zeinab Pourhadi,

Published: 17.12.2025.

Contents

17.12.2025. Review article
ANTI-INFLAMMATORY EFFECT OF BILBERRY (VACCINIUM MYRTILLUS L.) PREPARATION: A SYSTEMATIC REVIEW

Naturally-derived anti-inflammatories, such as bilberry (Vaccinium myrtillus), are particularly interesting due to their health benefits. Bilberries are a rich source of primary metabolites such as sugars and organic acids, which give the fruit its taste. They also contain anthocyanins, the most abundant group of secondary metabolites, possessing v...

By ANĐELA V. DRAGIĆEVIĆ, NIKOLA M. STOJANOVIĆ, DRAGANA R. PAVLOVIĆ

17.12.2025. Review article
EXPLORING USABILITY, SAFETY, AND PRELIMINARY EFFICACY OF NOVEL DIGITAL INTERVENTIONS IN ADOLESCENT PSYCHOTHERAPY: A NARRATIVE REVIEW

Artificial intelligence (AI) is increasingly recognized as a novel tool in enhancing psychotherapy, particularly for adolescents. The integration of AI-based platforms into mental health care promises improved accessibility, personalized interventions, and support for therapeutic processes. We aimed to evaluate the usability, safety, and preliminar...

By MIODRAG STANKOVIĆ, ALEKSANDRA STOJANOVIĆ

17.12.2025. Review article
EPILEPSY IN CHILDREN WITH CENTRAL NERVOUS SYSTEM INFECTIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS

In childhood, infections of the central nervous system may lead to neurodevelopmental disorders and complications such as epilepsy. The present study aimed to evaluate epilepsy in children with central nervous system (CNS) infections. The present systematic review and meta-analysis included five cohort studies from international databases, PubMed, ...

By MAHSA AFRAND, NIUSHA ROSTAMPUR, ZEINAB POURHADI, JAVAD REZANEZHAD, POURIYA NEKOUEIFARD

17.12.2025. Original article
EFFECT OF A SUBANESTHETIC DOSE OF KETAMINE ON AWAKENING AND POSTOPERATIVE DEPRESSION AND ANXIETY IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY

The present study was performed to evaluate the effect of subanesthetic dosage of ketamine on awakening and anxiety and depression status among patients undergoing coronary bypass graft (CABG) surgery. In this quasi-experimental study, 50 patients scheduled for elective CABG in a tertiary referral hospital were enrolled. Participants were allocated...

By RASOOL FERASATKISH, NAHID AGHDAII, ALI SADEGHI, MOHSEN ZIYAEIFARD, RASOUL AZARFARIN, MIRAHMAD HENDINEZHAD, ANAHITA BABAEI

17.12.2025. Original article
PROTECTIVE EFFECTS OF GREEN TEA AND BILBERRY AGAINST SECONDARY HYPERLIPIDEMIA IN GENTAMICIN‒INDUCED NEPHROTOXICITY IN RATS

The aim of this study was to examine whether green tea and bilberry have beneficial effects on secondary hyperlipidemia developed due to gentamicin-induced renal impairment. GM group of rats was treated with gentamicin only, GT group was given green tea only, B group received bilberry only, while C group was given saline only. GT+GM group received ...

By MILICA VELJKOVIĆ, NIKOLA M. STOJANOVIĆ, TANJA DŽOPALIĆ, DRAGANA R. PAVLOVIĆ, DUŠAN SOKOLOVIĆ, MILAN PETKOVIĆ

17.12.2025. Original article
PARAMETERS OF OXIDATIVE STRESS IN PATIENTS WITH BENIGN PROSTATE HYPERPLASIA, CHRONIC PROSTATITIS, AND PROSTATE CANCER

Benign prostatic hyperplasia (BPH), chronic prostatitis (CP), and prostate cancer (PC) are frequently occurring conditions that affect the prostate gland, with overlapping clinical features and potentially shared pathogenetic mechanisms. A growing body of research indicates that oxidative stress (OS) is a critical factor in both the onset and advan...

By ANDREJ VELJKOVIĆ, JOVAN HADŽI-ĐOKIĆ, DRAGOSLAV BAŠIĆ, LJUBOMIR DINIĆ, ALEKSANDAR SKAKIĆ, NINA MEDOJEVIĆ, OGNJEN RADOVIĆ, STEFANOS ROUMELIOTIS, KONSTANTINOS LEIVADITIS, GORDANA KOCIĆ

17.12.2025. Original article
CHARACTERISTICS AND MANAGEMENT OF PATIENTS WITH MULTIPLE MYELOMA: A SINGLE-CENTER EXPERIENCE

Multiple myeloma is the second most common hematological malignancy in which pathological plasma cells secrete monoclonal proteins, ultimately leading to end-organ damage. Albumin, β2-microglobulin, and LDH are considered highly relevant biomarkers for the diagnosis and prognosis of this disease. There are different types of treatment availabl...

By INA KONSTANTINOVIĆ, IRENA ĆOJBAŠIĆ, MIODRAG VUČIĆ

17.12.2025. Original article
NUTRITIONAL KNOWLEDGE AMONG PROSPECTIVE HEALTHCARE PROFESSIONALS

Unhealthy eating habits and a lack of physical activity are well-known risk factors for chronic illnesses, and many countries in transition have struggled to make significant progress in addressing diet-related non-communicable diseases. Education about diet and nutrition is important for public health, and healthcare professionals are essential in...

By BOJANA MILADINOVIĆ, MILICA MILUTINOVIĆ, DUŠANKA KITIĆ, MILICA RANDJELOVIĆ, NIKOLINA SAVIĆ, KATARINA SIMONOVIĆ, MAJA NIKOLIĆ

17.12.2025. Original article
DIAGNOSTIC ACCURACY OF IMMATURE PLATELET FRACTION PARAMETERS IN DISTINGUISHING IMMUNE THROMBOCYTOPENIC PURPURA FROM HYPOPRODUCTIVE THROMBOCYTOPENIA IN PEDIATRIC PATIENTS: A CROSS-SECTIONAL STUDY

Immune thrombocytopenic purpura (ITP) is a common cause of thrombocytopenia in pediatric patients, often requiring differentiation from hypoproductive thrombocytopenia. This study assesses the diagnostic accuracy of immature platelet fraction (IPF) parameters in distinguishing ITP from hypoproductive thrombocytopenia. A cross-sectional study was co...

By SHAHLA ANSARI, ZAHRA SOHEILIRAD

17.12.2025. Original article
VITILIGO-LIKE DEPIGMENTATION AS A PREDICTOR OF PROLONGED RESPONSE TO IMMUNE CHECKPOINT INHIBITORS IN PATIENTS WITH ADVANCED MELANOMA: A SINGLE-CENTER EXPERIENCE

Immune checkpoint inhibitors (ICIs) immensely improved outcomes in melanoma patients. Vitiligo-like depigmentation (VLD) is a well-documented adverse event of ICIs which is well tolerated and often associated with prolonged response to treatment. The aim of this study was to assess the effect of VLD occurrence on survival in melanoma patients treat...

By ALEKSANDAR POPOVIĆ, ANA STOJKOVIĆ, ANA CVETANOVIĆ, ANDRIJA JOVIĆ, MILICA RADIĆ, IRENA CONIĆ, IVAN PETKOVIĆ

17.12.2025. Original article
CRUCIAL ROLE OF PARENTS’ ENGAGEMENT IN SCHOOL-BASED HEALTH EDUCATION

Health education programs implemented in schools in Serbia should be improved methodologically with special emphasis on intersectoral action and inter-organizational partnerships at all levels, which implies identifying the role of children, teachers, parents, and all community representatives. The aim of our study was to define and analyze the rol...

By ROBERTA MARKOVIĆ

17.12.2025. Original article
IMPACT OF HEALTH LITERACY AND SEXUAL BEHAVIOUR ON UNPLANNED PREGNANCY AND ABORTION

It has been proven that health education is directly related to numerous decisions of young people regarding their reproductive health and sexual behavior. The aim of this paper is to evaluate the impact of health literacy and sexual behavior on the occurrence of unplanned pregnancies and abortions among young girls. We used STOFHLA to assess the h...

By MILENA MARIČIĆ, VANJA PAŽUN, VERICA TRBOVIĆ, KATARINA PAVLOVIĆ JUGOVIĆ, DANIJELA JEZDIMIROVIĆ, JOVANA MILOSAVLJEVIĆ, MILOŠ STEPOVIĆ

17.12.2025. Case report
SEAT BELT SYNDROME: THYROID CARTILAGE FRACTURE

Seat belt syndrome (SBS) is a new pattern of injuries in road traffic accidents (RTAs). It refers to injuries caused by the interaction of the human body and the safety belt and consists of a wide spectrum of injuries (musculoskeletal and visceral). In this paper, we present a case of a front-seat passenger with polytrauma sustained in an RTA, who,...

By SLAĐANA ANĐELIĆ, ELEFTHERIA PAPADOPOULOU, TANJA NIKOLIĆ, GORAN ČOLAKOVIĆ, MILENA POPOVIĆ

17.12.2025. Case report
BEHСET’S DISEASE WITH RECURRENT APHTHOUS STOMATITIS, POLYARTHRALGIA, AND SUPERFICIAL VEINS THROMBOSIS

Behçet’s disease is a systemic, chronic, idiopathic inflammatory illness of unknown etiology with a recurrent course, manifested by a characteristic triad: recurrent aphthous stomatitis, ulcerative changes in the mucous membranes and skin of the genital organs, and inflammatory changes in the eyes. In addition, the musculoskeletal syst...

By VITA RUZHANSKA, IULIIA PASHKOVA, DMYTRO GREBENIUK, ANDRII SIDOROV, SVITOZAR PREVAR, OLEKSANDR SMIIUKHA, YURIY HNATIYK, ARINA IVANITSA

17.12.2025. Case report
ISOLATED RIGHT FALLOPIAN TUBE TORSION IN A 13-YEAR-OLD ADOLESCENT

Isolated  fallopian tube torsion is a rare condition, especially in adolescents, and can often be misdiagnosed due to nonspecific symptoms. We report the case of a 13-year-old sexually inactive girl who was admitted to Shahid Mobini Hospital in Sabzevar, Iran, with worsening pain in the right lower abdomen and hypogastrium over the past four d...

By BEHNAZ SOUIZI, MEHRNAZ MEHRDOOST, MARZIE TORKMANNEJAD SABZEVARI, NARJES FOROUHAR

17.12.2025. Notes
RETRACTION NOTE: “CYSTIC DUCT WITH MEDIAL SPIRAL INSERTION” (Vol. 42, No. 3, p. 417–421) by Ilija Golubović, Aleksandar Vukadinović, Nebojša S. Ignjatović, Miroslav Stojanović

Retraction Note This article has been retracted post-publication at the request of the corresponding author due to an unresolved authorship dispute. Concerns were raised regarding changes made to the authorship list after the initial submission, specifically the removal of an author whose name appeared in the original submission and the addition o...

By AFMN BIOMEDICINE EDITORIAL BOARD

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