Vascularization, proliferative activity and the p53 status in glioblastomas
Glioblastomas (GBMs) are among the most vascularized human tumors and the presence of microvascular proliferation is one of the diagnostic hallmarks of these malignancies. The aim of the present study was to investigate the extent of vascularization and its relation to proliferative activity and the p53 status in GBMs. Tissue samples from 100 selec...
By Desanka Tasić, Irena Dimov, Miloš Kostov, Dragan Dimov
Hepatorenal toxicity of different doses of ketorolac administration in adult male rats: A preclinical study
Ketorolac is a potent non-steroidal anti-inflammatory drug (NSAID) that can inhibit cyclooxygenase activity and prostaglandin synthesis, thereby reducing pain and inflammation. The aim of this study was to investigate the hepatorenal toxicity of ketorolac administration in adult male rats. Twenty-four adult male Wistar rats were randomly assigned t...
By Fatemeh Rashidi, Amir Noyani, Salma Omidi, Touraj Assadi
N-terminal pro-brain natriuretic peptide superiority for prognosis of major adverse cardiovascular events in patients with acute myocardial infarction without heart failure
Many markers are used to evaluate the prognosis in patients with acute myocardial infarction (AMI). Researches are focused on available markers with high sensitivity and specificity. The aim of our study was to evaluate the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and its superiority compared with other prognostic ma...
By Rada Vučić, Vladimir Ignjatović, Olivera Andrejić, Katarina Čupić, Miodrag Srećković, Filipović Vučković, Marija Sekulić, Milan Dobrić, Jelena Rakočević
PROTECTIVE EFFECTS OF GREEN TEA AND BILBERRY AGAINST SECONDARY HYPERLIPIDEMIA IN GENTAMICIN‒INDUCED NEPHROTOXICITY IN RATS
The aim of this study was to examine whether green tea and bilberry have beneficial effects on secondary hyperlipidemia developed due to gentamicin-induced renal impairment. GM group of rats was treated with gentamicin only, GT group was given green tea only, B group received bilberry only, while C group was given saline only. GT+GM group received ...
By Milica Veljković, Nikola M. Stojanović, Tanja Džopalić, Dragana R. Pavlović, Dušan Sokolović, Milan Petković
ANTI-INFLAMMATORY EFFECT OF BILBERRY (VACCINIUM MYRTILLUS L.) PREPARATION: A SYSTEMATIC REVIEW
Naturally-derived anti-inflammatories, such as bilberry (Vaccinium myrtillus), are particularly interesting due to their health benefits. Bilberries are a rich source of primary metabolites such as sugars and organic acids, which give the fruit its taste. They also contain anthocyanins, the most abundant group of secondary metabolites, possessing v...
By Anđela V. Dragićević, Nikola M. Stojanović, Dragana R. Pavlović
Giant epithelial cysts of the spleen in children: Report of two cases and mini literature review
Cystic changes of the spleen are one of the rare clinical entities in the pediatric population. The paper presents a partial splenectomy in children performed by open approach as a safe surgical treatment of giant epithelial splenic cysts. Two cases of giant epithelial cysts of the spleen in children are presented. Medical documents and data referr...
By Maja Zečević, Zoran Marjanović, Dragoljub Živanović, Goran Janković, Nikola Živković, Živojin Spasić, Strahinja Konstantinović
The Modern Concept of Etiopathogenesis and Diagnosis of Shock
Shock is a life-threatening condition that occurs due to a mismatch in the supply and consumption of oxygen, which leads to cell and tissue hypoxia, resulting in cell death and dysfunction of vital organs. The effects of shock are reversible in the early stages, but delay in diagnosis and initiation of treatment can lead to irreversible changes. Th...
By Uroš Ristić, Radmilo Janković, Marija Stošić, Milan Manić, Jelena Živadinović, Dalibor Stojanović, Biljana Stošić
ERRATUM - TREATMENT OF BURN INJURIES IN CHILDREN
This erratum is published to address inaccuracies in the first affiliation of the author of the above-mentioned article. The first affiliation, as presented on the title page, the last page, and within the abstract in Serbian, was not cited consistently. In addition, the official name of the clinic changed shortly after the article’s publicat...
By Acta Facultatis Medicae Naissensis Editorial Board
The application of artificial intelligence in the healthcare system management in the Republic of Serbia: Enhancing efficiency, predictive capacity, and decision-making
Artificial intelligence (AI) offers transformative potential in healthcare management by enhancing predictive analytics, optimizing resource allocation, and supporting clinical decision-making. This study aims to examine the applications of AI in Serbian healthcare institutions, focusing on improving operational efficiency and patient outcomes. The...
By Milić Kimi, Šćepan Sinanović, Tatjana Kilibarda, Saša Bubanj, Novica Bojanić, Tanja Prodović
Splenic abscess due to Salmonella enteritidis after abdominal trauma resolved by interventional radiological methods: A case report
Splenic abscess is a very rare extra-intestinal complication of Salmonella infection in the post-antibiotic era with the incidence between 0.14% and 2%. It usually follows bacteremia due to varied etiologies such as trauma, infective endocarditis, intravenous drug abuse, immunodeficiency status (AIDS, diabetes mellitus). An 82-year-old woman presen...
By Milan Pantelić, Tamara Vučinić, Milica Stanucević, Miloš Dujović, Maša Pantelić