FH is an autosomal dominant disease of lipid metabolism. Hypercholesterolemia, xanthomas, and death from early coronary artery disease (CAD) are common in this disease due to a mutation in the LDLR, Apo-B100 or PCSK9 genes. A 4-year-old male patient with a very rare heterozygous c.1730G > C (p.Trp577Ser) variation in exon 12 of the low-density l...

By Mustafa Doğan, Mehmet Koksal, Recep Eroz

Oxidative stress and resulting lipid peroxidation are involved in numerous pathological conditions. For this reason, the role of antioxidants attracts attention and the radical-scavenging capacity of many natural and synthetic supplements and drugs has been extensively evaluated. In the present study, seven N,N'-disubstituted benzimidazole-2-thione...

By Jelena Lazarević, Jelena Zvezdanović, Neda Anastassova, Anelia Mavrova, Denitsa Yancheva, Andrija Šmelcerović

The aim of the study was to examine the relationship between noise exposure and the incidence of arterial hypertension as well as the relationship of noise annoyance and noise sensitivity with hypertension. A cross-sectional questionnaire survey was performed on 911 adult residents of Niš, Serbia, of whom 388 were men (42.6%) and 523 women (...

By Ljiljana Stošić, Dušica Stojanović, Konstansa Lazarević

Toxoplasmosis modifies various hormones and cytokines in the infected hosts which may result in several disorders. This study was conducted to assess testosterone, DHEA, and prolactin concentration levels among Toxoplasma gondii infected and uninfected infertile couples. Blood samples were collected and sera were separated. The sera were analyzed f...

By Masomeh Bayani, Narges Kalantari, Sedigheh Esmailzadeh, Salman Ghaffari, Soleiman Mahjoub, Faezeh Ghofrani, Taraneh Ghaffari

Varicella zoster virus is a highly infectious a-herpesvirus, pathogenic only to humans. The primary infection of varicella zoster virus causes chickenpox, which is contagious and primarily infects children and adolescents in India. Following the primary infection, the virus remains dormant in sensory root ganglia. Activation of the dormant virus in...

By Varshini Marimuthu, Dinakar Jayakumar, Gowri Shanmugasundaram

The chief aim of this study was monitoring of laboratory parameters of chronic kidney failure in elderly patients. All samples were taken and processed by standard methods and according to the principles of good laboratory practice. Data were collected in an organized and systematic manner in the form of a questionnaire with respect to ethical prin...

By Edhem Hasković, Harun Uzunalıć, Snežana Unčanin, Safija Herenda, Denis Hasković, Amina Selimović

Texture profile analysis, as the most popular method of texture analysis today, is used for relating the mechanical characteristics of the samples to their sensory characteristics. Thickeners have an important influence on the mechanical properties of semi-solid products, and thus on the physical stability of creams. Choosing the right one often re...

By Aleksandra Stolić-Jovanović, Milica Martinović, Ivana Nešić

Bullous pemphigoid (BP) is an autoimmune skin disease that typically presents with severe itching and blistering, with or without eczematous and urticarial lesions. Patients with BP are at an increased risk of comorbid conditions, especially neurologic and psychiatric diseases. Several recent studies have found a link between BP and neurological di...

By Arsovska Mirceska, Katerina Damevska, Viktor Simeonovski, Andrija Jović, Danica Tiodorović

Graves' disease is an autoimmune thyroid disease that is the most common cause of hyperthyroidism. Peripheral blood cell parameters such as neutrophils, lymphocytes, and platelets play a role in inflammation control. Several studies have proven that neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio and platelet-lymphocyte ratio are indicators ...

By Aksanur Gokce, Tulay Omma, Mustafa Çelikc, Işılay Taşkaldıran

Lung cancer is the leading cause of mortality from cancer across the world. In this study, the use of serum nucleolin (NCL) and nucleophosmin (NPM1) levels as a marker in the diagnosis, prognosis and treatment response evaluation in lung cancer was investigated. NCL and NPM1 levels of serum samples taken before chemotherapy and after 3-4 courses of...

By Gül Akın, Onur Esbah, Recep Eröz