Remodeling of the myocardium in patients with primary aldosteronism (PA) is mediated by the presence of mineralocorticoid receptors on the myocytes and fibroblasts. The goal of this study was to analyze the effect of arterial hypertension and metabolic disorders on the cardiovascular system in patients with PA. We recruited 54 patients with PA, 32 ...

By Andryi Nykonenko, Iryna Zubryk, Oleksandr Podluzhnyi, Olrksandr Molodan, Sergii Bukhtii, Oleksandr Nykonenko

The use of maggot therapy (MT) is proving effective in the treatment of complicated diabetic foot ulcers (DFUs). Most of the previous studies have focused on the comparison of MT and routine treatment approaches for the management of DFUs. The aim of this study was to add MT to routine treatment line of DFUs as a new approach. In this study, the pr...

By Omid Dehghan, Tabaie Mehdi, Javad Rafinejad, Mehrangiz Toutonnchy, Amir Tiyuri, Kamran Akbarzadeh, Haghi Motevalli

Pelvis is a strong bony-ligamentous structure containing many organs, vessels and nerves. Three forces or a combination of those forces produce pelvic fractures. The main causes of pelvic fractures are traffic accidents and falls from height. Biomechanically pelvic ring can be stable or unstable. Biomechanically unstable pelvic ring after the injur...

By Saša Milenković, Milan Mitković

Antioxidant properties of 2-[2-imino-5-nitro-3-(2-oxo-2-phenylethyl)-2,3-dihydro-1H-benzimidazol1-yl]-1-phenylethanone (compound 1) and 2-(4-fluorobenzylidene)-6-(phenylcarbonyl)[1,3]thiazolo[3,2a]benzimidazol-3(2H)-one (compound 2) were evaluated in vitro. Compounds 1 and 2 did not show significant radical scavenging activity. It has been suggeste...

By Katarina Tomović, Jelena Mrmošanin, Denitsa Yancheva, Anelia Mavrova, Andrija Šmelcerović

Normal development is one of the reliable criteria for the assessment of children's health status. Perinatal events affect the future development of children. Nevertheless, there are different views on the impact of events in the perinatal period on child development. The aim of this study was to determine the relationship between perinatal period ...

By Masoumeh Kaviani, Zhaleh Ranjbaran, Roksana Janghorban

Considerable share of patients admitted to the intensive care unit, during the current Covid-19 pandemic, are obese. Obesity is associated with chronic low-grade inflammation, higher endothelial injury, higher levels of angiotensinogen II and increased expression of angiotensin-converting enzyme 2 receptors in the adipose tissue. These alterations ...

By Vesna Marjanović

Teeth are biological markers of maturity, and their eruption into the oral cavity is an essential milestone in an individual's life. Multiple factors have been considered to play a role in the pattern of tooth eruption, including dental caries, fluorides and congenital conditions such as Down's syndrome. The aim of the paper was to determine the ti...

By Varshini Marimuthu, Pushparaja Shetty

Poor oral hygiene and diseases of the teeth and oral tissues can affect all aspects of patients' lives. The aim of the study was to determine the subjective assessment of oral and general health and their impact on the quality of life in elderly patients. The research included 46 patients, geriatric center users, who were asked questions from a thr...

By Milena Kostić, Marko Igić, Ana Pejčić

Oxidative stress, as one of the pathophysiological mechanisms involved in the reduction of myocardial contractility, stimulates the proliferation of cardiac fibroblasts and the activation of matrix metalloproteinases, which leads to extracellular matrix remodeling. Left ventricular hypertrophy (LVH) is a well-known independent risk factor for cardi...

By Sandra Šarić, Tatjana Cvetković, Dejan Petrović, Valentina Mitić, Sanja Stojanović, Vladana Stoiljković, Marina Deljanin-Ilić

Achilles tendon injuries most commonly occur in athletes, but also in the middle-aged population practicing recreational sports. The aetiology of injury and disease of the Achilles tendon has not been completely clarified. While acute injury can be attributed to trauma, research showed that a chronic degenerative process is present in most ruptures...

By Mihajlo Mitrović, Dražen Jelača, Ivana Mitrović